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Compound 1T-0219 (SC)

🥰Excellent
Catalog No. T9545Cas No. 383147-92-0

Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.

Compound 1T-0219 (SC)

Compound 1T-0219 (SC)

🥰Excellent
Catalog No. T9545Cas No. 383147-92-0
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
Pack SizePriceAvailabilityQuantity
1 mg$148In Stock
5 mg$336In Stock
10 mg$497In Stock
25 mg$793In Stock
50 mg$1,130In Stock
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Product Introduction

Bioactivity
Description
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.
Chemical Properties
Molecular Weight413.38
FormulaC20H19N3O7
Cas No.383147-92-0
SmilesCOC1=CC=C(C=C1)C(=O)O\N=C1/CCCCC1C1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O
Relative Density.1.40 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5 mg/mL (12.1 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4191 mL12.0954 mL24.1908 mL120.9541 mL
5 mM0.4838 mL2.4191 mL4.8382 mL24.1908 mL
10 mM0.2419 mL1.2095 mL2.4191 mL12.0954 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Compound 1T0219 (SC)Compound 1T-0219Compound 1T0219Compound 1T 0219 (SC)Compound 1T 0219AKT1-FAK
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