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Anti-FOXP3 Antibody (2R607)
😃Good
Catalog No. TMAY-01586
Anti-FOXP3 Antibody (2R607) is a Mouse antibody targeting FOXP3. Anti-FOXP3 Antibody (2R607) can be used in IHC-P.
Anti-FOXP3 Antibody (2R607)
Anti-FOXP3 Antibody (2R607)
😃Good
Catalog No. TMAY-01586
Anti-FOXP3 Antibody (2R607) is a Mouse antibody targeting FOXP3. Anti-FOXP3 Antibody (2R607) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Ig Type | mouse IgG2a |
| Clone | 2R607 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human FOXP3 in human carcinoma of sigmoid with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human FOXP3. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Forkhead box P3 (FOXP3) is a key gene in the immune system which also plays a role in tumor development. The Treg cell lineage-specification factor FOXP3 (forkhead box P3) is essential for Treg cells' ability to uphold immunologic tolerance. Forkhead box protein 3 (FOXP3) is expressed in numerous types of tumor cell and is associated with tumor progression and prognosis. which had been reported that FOXP3 inhibited cellular proliferation and induced apoptosis of gastric cancer (GC) cells by activating the apoptosis signaling pathway. The elevated expression of FOXP3 in blood and urine samples from kidney transplant recipients could be a useful noninvasive biomarker to diagnose graft dysfunction. Forkhead box P3 (FOXP3), an X-linked tumor suppressor gene, plays an important role in breast cancer. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: center region of the Human FOXP3 |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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