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Anti-SYNCRIP Antibody (3C999)

(Synonyms: Synaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein) Copy Product Info
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Synonyms: Synaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein

Catalog No. TMAC-01998 Copy Product Info
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Anti-SYNCRIP Antibody (3C999) is a Rabbit antibody targeting SYNCRIP. Anti-SYNCRIP Antibody (3C999) can be used in ICC,IF,IHC,WB.
Anti-SYNCRIP Antibody
(3C999)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SYNCRIP Antibody (3C999) is a Rabbit antibody targeting SYNCRIP. Anti-SYNCRIP Antibody (3C999) can be used in ICC,IF,IHC,WB.
SynonymsSynaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein
Ig Type
IgG
Clone
3C999
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPre-mRNA splicing is a critical step in the posttranscriptional regulation of gene expression. Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) is involved in RNA processing and is necessary for efficient pre-mRNA splicing. hnRNP is widely expressed and developmentally regulated. hnRNP Q interacts with survival motor neuron protein (SMN). Loss of function of SMN results in spinal muscular atrophy, a common neurodegenerative disease. The most common deletion in SMN genes disrupts the interaction between SMN and hnRNP Q. hnRNP Q is upregulated after midnight, and this upregulation correlates with an abrupt decline in AANAT, the key enzyme in melatonin synthesis. Rhythmic AANAT mRNA degradation mediated in part by hnRNP Q implicates this enzyme in the regulation of circadian oscillation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: C-terminal human hnRNP Q
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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