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Anti-SYNCRIP Antibody (3C999)
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Catalog No. TMAC-01998
Alias Synaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein
Anti-SYNCRIP Antibody (3C999) is a Rabbit antibody targeting SYNCRIP. Anti-SYNCRIP Antibody (3C999) can be used in ICC,IF,IHC,WB.
Anti-SYNCRIP Antibody (3C999)
Anti-SYNCRIP Antibody (3C999)
😃Good
Catalog No. TMAC-01998Alias Synaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein
Anti-SYNCRIP Antibody (3C999) is a Rabbit antibody targeting SYNCRIP. Anti-SYNCRIP Antibody (3C999) can be used in ICC,IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SYNCRIP Antibody (3C999) is a Rabbit antibody targeting SYNCRIP. Anti-SYNCRIP Antibody (3C999) can be used in ICC,IF,IHC,WB. |
| Synonyms | Synaptotagmin-binding, NSAP1, NS1-associated protein 1, HNRPQ, hnRNP Q, Heterogeneous nuclear ribonucleoprotein Q, GRY-RBP, Glycine- and tyrosine-rich RNA-binding protein, cytoplasmic RNA-interacting protein |
| Ig Type | IgG |
| Clone | 3C999 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of hnRNP Q on K562 cell lysate using anti-hnRNP Q antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin. 6. ICC staining hnRNP Q in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining hnRNP Q in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.        |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Pre-mRNA splicing is a critical step in the posttranscriptional regulation of gene expression. Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) is involved in RNA processing and is necessary for efficient pre-mRNA splicing. hnRNP is widely expressed and developmentally regulated. hnRNP Q interacts with survival motor neuron protein (SMN). Loss of function of SMN results in spinal muscular atrophy, a common neurodegenerative disease. The most common deletion in SMN genes disrupts the interaction between SMN and hnRNP Q. hnRNP Q is upregulated after midnight, and this upregulation correlates with an abrupt decline in AANAT, the key enzyme in melatonin synthesis. Rhythmic AANAT mRNA degradation mediated in part by hnRNP Q implicates this enzyme in the regulation of circadian oscillation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: C-terminal human hnRNP Q |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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