CCL28 Protein, Human, Recombinant

Name: CCL28 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00019
Rating: 4.5 (1 reviews)

(Synonyms: Small-Inducible Cytokine A28, SCYA28, Protein CCK1, Mucosae-Associated Epithelial Chemokine, MEC, CCL28, C-C Motif Chemokine 28) Copy Product Info

Synonyms: Small-Inducible Cytokine A28, SCYA28, Protein CCK1, Mucosae-Associated Epithelial Chemokine, MEC, CCL28, C-C Motif Chemokine 28

Catalog No. TMPJ-00019 Copy Product Info

Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.

Pack Size	Price	USA Stock	Global Stock
5 µg	$88	35 days	35 days
10 µg	$143	35 days	35 days
20 µg	$229	35 days	35 days
50 µg	$433	35 days	35 days
100 µg	$633	35 days	35 days
200 µg	$925	35 days	35 days
500 µg	$1,530	35 days	35 days
1 mg	$2,180	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q9NRJ3
Amino Acid	Ser20-Tyr127
Construction	Ser20-Tyr127
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Small-Inducible Cytokine A28, SCYA28, Protein CCK1, Mucosae-Associated Epithelial Chemokine, MEC, CCL28, C-C Motif Chemokine 28
Research Background	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.

Chemical Properties

Molecular Weight

15 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.