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CCL28 Protein, Human, Recombinant

Catalog No. TMPJ-00019
Synonyms: Small-Inducible Cytokine A28, Protein CCK1, CCL28, SCYA28, C-C Motif Chemokine 28, Mucosae-Associated Epithelial Chemokine, MEC

Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CCL28 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 143.00
50 μg 5 days $ 434.00
500 μg 5 days $ 1,530.00
1 mg 5 days $ 2,180.00
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Biological Description
Technical Params
Product Properties
Description Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
Species Human
Expression System E. coli
Tag None
Accession Number Q9NRJ3
Synonyms Small-Inducible Cytokine A28, Protein CCK1, CCL28, SCYA28, C-C Motif Chemokine 28, Mucosae-Associated Epithelial Chemokine, MEC
Amino Acid Ser20-Tyr127
Construction Recombinant Human C-C Motif Chemokine 28 is produced by our E.coli expression system and the target gene encoding Ser20-Tyr127 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 15 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.

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Keywords

CCL28 Protein, Human, Recombinant Small-Inducible Cytokine A28 CCL 28 Protein CCK1 SCYA 28 CCL-28 CCL28 SCYA-28 SCYA28 C-C Motif Chemokine 28 Mucosae-Associated Epithelial Chemokine MEC recombinant recombinant-proteins proteins protein

 

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