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Synonyms: SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-HNRNPC Antibody (6O738) is an antibody targeting HNRNPC. Anti-HNRNPC Antibody (6O738) can be used in ELISA,FCM,IF,IHC,IP,WB. |
| Synonyms | SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1 |
| Ig Type | Rabbit IgG |
| Clone | 6O738 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200; IP:1:200-1:1000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Note=Component of ribonucleosomes. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human HNRNPC |
| Antigen Species | Human |
| Gene Name | HNRNPC |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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