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Anti-HNRNPC Antibody (6O738)

(Synonyms: SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1) Copy Product Info
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Synonyms: SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1

Catalog No. TMAH-00563 Copy Product Info
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Anti-HNRNPC Antibody (6O738) is an antibody targeting HNRNPC. Anti-HNRNPC Antibody (6O738) can be used in ELISA,FCM,IF,IHC,IP,WB.
Anti-HNRNPC Antibody
(6O738)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HNRNPC Antibody (6O738) is an antibody targeting HNRNPC. Anti-HNRNPC Antibody (6O738) can be used in ELISA,FCM,IF,IHC,IP,WB.
SynonymsSNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1
Ig Type
Rabbit IgG
Clone
6O738
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200; IP:1:200-1:1000.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Note=Component of ribonucleosomes.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundBinds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human HNRNPC
Antigen Species
Human
Gene Name
HNRNPC
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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