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Anti-ABCA1 Polyclonal Antibody (Synonyms: TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958|...)
Catalog No. TMAB-00019 Copy Product Info
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Anti-ABCA1 Polyclonal Antibody is a Rabbit antibody targeting ABCA1. Anti-ABCA1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-ABCA1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00019
Synonyms TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1
Anti-ABCA1 Polyclonal Antibody is a Rabbit antibody targeting ABCA1. Anti-ABCA1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-ABCA1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ABCA1 Polyclonal Antibody is a Rabbit antibody targeting ABCA1. Anti-ABCA1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow,Horse) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCA1) Polyclonal Antibody, Unconjugated (TMAB-00019) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely expressed, but most abundant in macrophages. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019] |
| Immunogen | KLH conjugated synthetic peptide: human ABCA1 |
| Antigen Species | Human |
| Gene Name | ABCA1 |
| Gene ID | |
| Protein Name | phospholipid-transporting ATPase ABCA1 |
| Uniprot ID | |
| Biology Area | Metabolism of lipids and lipoproteins,Lipoprotein metabolism,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Lipoprotein metabolism,Cancer,Heart disease,Astrocyte marker,Lipid metabolism |
| Function | cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport. |
| Molecular Weight | Theoretical: 254 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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