Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Cystatin B Antibody-HRP (7I934)

😃Good
Catalog No. TMAY-00827H
Alias ULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6

Anti-Cystatin B Antibody-HRP (7I934) is a HRP-conjugated Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody-HRP (7I934) can be used in ELISA.

Anti-Cystatin B Antibody-HRP (7I934)

Anti-Cystatin B Antibody-HRP (7I934)

😃Good
Catalog No. TMAY-00827HAlias ULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6
Anti-Cystatin B Antibody-HRP (7I934) is a HRP-conjugated Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody-HRP (7I934) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μg$293 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Cystatin B Antibody-HRP (7I934) is a HRP-conjugated Mouse antibody targeting Cystatin B. Anti-Cystatin B Antibody-HRP (7I934) can be used in ELISA.
AliasULD, STFB, PME, EPM1A, EPM1, cystatin B (stefin B), CST6
Ig Type
Monoclonal Mouse IgG2a
Clone
7I934
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin B / CSTB (rh Cystatin B / CSTB; TMPY-02090; P04080; Met 2-Phe 98). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family).
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human Cystatin B / CSTB protein (TMPY-02090)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-Cystatin B Antibody-HRP (7I934) | purchase Anti-Cystatin B Antibody-HRP (7I934) | Anti-Cystatin B Antibody-HRP (7I934) cost | order Anti-Cystatin B Antibody-HRP (7I934)