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Asatone

🥰Excellent

Catalog No. T10383Cas No. 38451-63-7

Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.

Asatone

🥰Excellent

Purity: 99.92%

Catalog No. T10383Cas No. 38451-63-7

Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.

Pack Size	Price	Availability
1 mg	$78	In Stock
5 mg	$188	In Stock
10 mg	$296	In Stock
25 mg	$513	In Stock
50 mg	$729	In Stock
100 mg	$985	In Stock
200 mg	$1,330	In Stock
1 mL x 10 mM (in DMSO)	$198	In Stock

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Batch Information

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Purity:99.92%

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Product Introduction

Bioactivity

Description

Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.

Chemical Properties

Molecular Weight	448.51
Formula	C₂₄H₃₂O₈
Cas No.	38451-63-7
Smiles	[H][C@]12C(CC=C)=C[C@](OC)(C(=O)C1(OC)OC)[C@@]1(CC=C)C=C(OC)C(=O)C(OC)(OC)[C@@]21[H]
Relative Density.	1.19 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (133.78 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2296 mL	11.1480 mL	22.2960 mL	111.4802 mL
5 mM	0.4459 mL	2.2296 mL	4.4592 mL	22.2960 mL
10 mM	0.2230 mL	1.1148 mL	2.2296 mL	11.1480 mL
20 mM	0.1115 mL	0.5574 mL	1.1148 mL	5.5740 mL
50 mM	0.0446 mL	0.2230 mL	0.4459 mL	2.2296 mL
100 mM	0.0223 mL	0.1115 mL	0.2230 mL	1.1148 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc