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IL-23R inhibitor peptide-1

Name: IL-23R inhibitor peptide-1
Brand: TargetMol
SKU: TP2870
Price: 299 USD
Availability: InStock
Rating: 5 (10 reviews)

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IL-23R inhibitor peptide-1 is a potent peptide antagonist of Interleukin-23 receptor (reported IC₅₀ ≈ 0.0069 μM). It inhibits IL-23 signaling by disrupting the interaction between IL-23 and its receptor and is used in studies of autoimmune and inflammatory mechanisms.

Cas No. 2894052-23-2

Pack Size	Price	USA Stock	Global Stock	Quantity
1 mg	$299	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	1897.18
Formula	C₉₁H₁₂₁N₁₉O₂₂S₂
Cas No.	2894052-23-2
Smiles	N(C([C@H](CC1=CC2=C(C=C1)C=CC=C2)NC([C@H](CC3=CC=C(OCCN)C=C3)NC(=O)[C@H]4NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC=5C=6C(NC5)=C(C)C=CC6)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(C)=O)C(C)(C)SSC4(C)C)[H])=O)=O)C7(C(N[C@H](C(N[C@H](C(N[C@@H](CC8=CC=CC=C8)C(N(CC(N)=O)C)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)CCOCC7
Sequence	Ac-Pen-Asn-Thr-(7Me)Trp-Lys(Ac)-Pen(AEF)-2Nal(THP)-Glu-Asn-Phe-Sar-NH₂ (Bridge:Pen1-Pen6)
Sequence Short	CNTWKCXENFX

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (21.08 mM)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.5271 mL	2.6355 mL	5.2710 mL	26.3549 mL
5 mM	0.1054 mL	0.5271 mL	1.0542 mL	5.2710 mL
10 mM	0.0527 mL	0.2635 mL	0.5271 mL	2.6355 mL
20 mM	0.0264 mL	0.1318 mL	0.2635 mL	1.3177 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: IL-23R inhibitor peptide-1 chemical structure | IL-23R inhibitor peptide-1 formula | IL-23R inhibitor peptide-1 molecular weight