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Anti-PODXL Monoclonal Antibody-Biotin (Synonyms: Podocalyxin-like protein 1, Podocalyxin, Gp200, GCTM-2 antig...)

Catalog No. TMAZ-0170B Copy Product Info
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Anti-PODXL Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting PODXL. Anti-PODXL Monoclonal Antibody-Biotin can be used in ELISA,FCM.

Anti-PODXL Monoclonal Antibody-Biotin

Copy Product Info
🥰Excellent
Catalog No. TMAZ-0170B
Synonyms Podocalyxin-like protein 1, Podocalyxin, Gp200, GCTM-2 antigen

Anti-PODXL Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting PODXL. Anti-PODXL Monoclonal Antibody-Biotin can be used in ELISA,FCM.

Anti-PODXL Monoclonal Antibody-Biotin
Pack SizePriceUSA StockGlobal StockQuantity
25 μg$19612 days12 days
50 μg$23612 days12 days
100 μg$33012 days12 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PODXL Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting PODXL. Anti-PODXL Monoclonal Antibody-Biotin can be used in ELISA,FCM.
SynonymsPodocalyxin-like protein 1, Podocalyxin, Gp200, GCTM-2 antigen
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of PODXL overexpressed 377F cells with TMAZ-0170B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA
FCM
Recommended Dose
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of PODXL protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in PBS.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundInvolved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells
Related Conjugates and Formulations
Conjucates
Biotin
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
PODXL
Antigen Species
Human
Gene ID
5420
Uniprot ID
O00592
Biology Area
Drug Target
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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