Mal-PEG2-Val-Cit-PABA-PNP

Name: Mal-PEG2-Val-Cit-PABA-PNP
Brand: TargetMol
SKU: T38739
Rating: 4.5 (1 reviews)

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Catalog No. T38739Cas No. 1345681-52-8

Alias Mal-PEG2-Val-Cit-PABA-PNP

Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound used in the synthesis of antibody-drug conjugates (ADCs).

Mal-PEG2-Val-Cit-PABA-PNP

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Catalog No. T38739Alias Mal-PEG2-Val-Cit-PABA-PNPCas No. 1345681-52-8

Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound used in the synthesis of antibody-drug conjugates (ADCs).

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound used in the synthesis of antibody-drug conjugates (ADCs).
In vitro	Antibody-drug conjugates (ADCs) consist of an antibody linked to an ADC cytotoxin via an ADC linker[1].
Synonyms	Mal-PEG2-Val-Cit-PABA-PNP

Chemical Properties

Molecular Weight	755.738
Formula	C₃₄H₄₁N₇O₁₃
Cas No.	1345681-52-8
Smiles	CC(C)[C@H](NC(=O)OCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)N(=O)=O)cc1 \|c:16\|
Relative Density.	1.380 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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