Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-5274857 hydrochloride is a potent, orally active, selective, blood-brain barrier permeable Smo antagonist with IC50=5.8 nM and Ki=4.6 nM. It has research potential in a variety of tumors including brain tumors and brain metastases driven by activated Hh pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | 35 days | $ 2,400.00 |
Description | PF-5274857 hydrochloride is a potent, orally active, selective, blood-brain barrier permeable Smo antagonist with IC50=5.8 nM and Ki=4.6 nM. It has research potential in a variety of tumors including brain tumors and brain metastases driven by activated Hh pathways. |
Targets&IC50 | Smo:5.8 nM (IC50), Smo:Ki: 4.6 nM |
Molecular Weight | 473.42 |
Formula | C20H26Cl2N4O3S |
CAS No. | 1613439-62-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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PF-5274857 hydrochloride 1613439-62-5 PF5274857 hydrochloride PF 5274857 Hydrochloride PF 5274857 hydrochloride PF-5274857 Hydrochloride PF5274857 Hydrochloride inhibitor inhibit