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Tezepelumab (Synonyms: Tezepelumab-ekko, MEDI 19929, AMG 157)

Catalog No. T77359 Copy Product Info
Purity: 95%
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Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.

Tezepelumab

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Catalog No. T77359
Synonyms Tezepelumab-ekko, MEDI 19929, AMG 157

Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.

Tezepelumab
Cas No. 1572943-04-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$1,060-In Stock
5 mg$2,320In StockIn Stock
10 mg$3,130-In Stock
25 mg$4,670-In Stock
50 mg$6,280-In Stock
100 mg$8,480-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.5% (SDS-PAGE); 99.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
In vitro
Tezepelumab blocks thymic stromal lymphopoietin, an epithelial cell-derived cytokine implicated in the pathogenesis of asthma[1].
SynonymsTezepelumab-ekko, MEDI 19929, AMG 157
Reactivity
Human
Verified Activity
Immobilized Human TSLP Protein (R127A, R130S, His) (TMPY-05220) at 1 μg/mL can bind Tezepelumab. The EC50 is 8.91 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTSLP
Chemical Properties
Molecular Weight144.58 kDa
Cas No.1572943-04-4
Antibody Information
IsotypeIgG2
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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