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Tezepelumab
(Synonyms: Tezepelumab-ekko, MEDI 19929, AMG 157) Copy Product Info
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Synonyms: Tezepelumab-ekko, MEDI 19929, AMG 157
Catalog No. T77359 Copy Product Info
Purity: 95%
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Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
Tezepelumab
Cas No. 1572943-04-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $1,060 | - | In Stock | |
| 5 mg | $2,320 | In Stock | In Stock | |
| 10 mg | $3,130 | - | In Stock | |
| 25 mg | $4,670 | - | In Stock | |
| 50 mg | $6,280 | - | In Stock | |
| 100 mg | $8,480 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.5% (SDS-PAGE); 99.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Chemical Properties
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| Description | Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease. |
| In vitro | Tezepelumab blocks thymic stromal lymphopoietin, an epithelial cell-derived cytokine implicated in the pathogenesis of asthma[1]. |
| Expression System | HEK293 |
| Endotoxin | <1.0 EU/mg |
| Synonyms | Tezepelumab-ekko, MEDI 19929, AMG 157 |
| Reactivity | Human |
| Verified Activity | Immobilized Human TSLP Protein (R127A, R130S, His) (TMPY-05220) at 1 μg/mL can bind Tezepelumab. The EC50 is 8.91 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TSLP |
| Molecular Weight | 144.58 kDa |
| Cas No. | 1572943-04-4 |
| Isotype | Human IgG2 lambda |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Tezepelumab in vitro | Tezepelumab molecular weight
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