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Anti-NUMA1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01275
Alias SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22
Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-NUMA1 Polyclonal Antibody
Anti-NUMA1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01275Alias SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22
Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Alias | SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (human breast); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NuMA) Polyclonal Antibody, Unconjugated (TMAB-01275) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Resides in the nuclear matrix during interphases. Dissociates from condensing chromosomes during early prophase, and relocates to the spindle poles via dynein/dynamin association, it remain there until the anaphase onset. Before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident. Isoform Numa-m: Cytoplasm. Note=Mainly clustered at the centrosomal region. Isoform Numa-s: Cytoplasm. Note=Mainly clustered at the centrosomal region. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Healthy individuals generally have very small amounts of NMP22 protein in the urine. However, the level of NMP22 protein is often elevated in the urine of patients with bladder cancer, even at early stages of the disease.1 The Alere NMP22 Test is an enzyme immunoassay for the quantitative determination of nuclear mitotic apparatus protein (NuMA) in stabilized voided urine. NuMA is an abundant component of the nuclear matrix proteins (NMP22). The Alere NMP22?BladderChek?Test is the only in-office test approved by the FDA as an aid in the diagnosis and monitoring of bladder cancer in conjunction with standard diagnostic procedures. Both assays are painless and non-invasive and detect elevated levels of NMP22 protein. |
| Immunogen | KLH conjugated synthetic peptide: human NuMA |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Spindle,Markers |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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