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Anti-NUMA1 Polyclonal Antibody

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Catalog No. TMAB-01275

Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NUMA1 Polyclonal Antibody

Anti-NUMA1 Polyclonal Antibody

😃Good
Catalog No. TMAB-01275
Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$222 7-10 days
100 μL$374 7-10 days
200 μL$527 7-10 days
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Product Introduction

Bioactivity
Description
Anti-NUMA1 Polyclonal Antibody is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (human breast); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NuMA) Polyclonal Antibody, Unconjugated (TMAB-01275) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Resides in the nuclear matrix during interphases. Dissociates from condensing chromosomes during early prophase, and relocates to the spindle poles via dynein/dynamin association, it remain there until the anaphase onset. Before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident. Isoform Numa-m: Cytoplasm. Note=Mainly clustered at the centrosomal region. Isoform Numa-s: Cytoplasm. Note=Mainly clustered at the centrosomal region.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundHealthy individuals generally have very small amounts of NMP22 protein in the urine. However, the level of NMP22 protein is often elevated in the urine of patients with bladder cancer, even at early stages of the disease.1 The Alere NMP22 Test is an enzyme immunoassay for the quantitative determination of nuclear mitotic apparatus protein (NuMA) in stabilized voided urine. NuMA is an abundant component of the nuclear matrix proteins (NMP22). The Alere NMP22?BladderChek?Test is the only in-office test approved by the FDA as an aid in the diagnosis and monitoring of bladder cancer in conjunction with standard diagnostic procedures. Both assays are painless and non-invasive and detect elevated levels of NMP22 protein.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NuMA
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Spindle,Markers
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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