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LJP-1586 HCl

Catalog No. T8857 CAS 955037-42-0

Synonyms: LJP-1586 hydrochloride

LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

LJP-1586 HCl, CAS 955037-42-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 195.00
5 mg	In stock	$ 449.00
10 mg	In stock	$ 675.00
25 mg	In stock	$ 995.00
50 mg	In stock	$ 1,450.00
100 mg	In stock	$ 1,950.00

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Purity: 99.4%

Purity: 99.06%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	LJP-1586 hydrochloride
Molecular Weight	231.69
Formula	C11H15ClFNO
CAS No.	955037-42-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

H2O: 40mg/mL, Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Filip A, et al. Expression of the semicarbazide-sensitive amine oxidase in articular cartilage: its role in terminal differentiation of chondrocytes in rat and human. Osteoarthritis Cartilage. 2016 Jul;24(7):1223-34. 2. Xu H, et al. VAP-1 blockade prevents subarachnoid hemorrhage-associated cerebrovascular dilating dysfunction via repression of a neutrophil recruitment-related mechanism. Brain Res. 2015 Apr 7;1603:141-9. 3. Xu HL, et al. Pharmacologic blockade of vascular adhesion protein-1 lessens neurologic dysfunction in rats subjected to subarachnoid hemorrhage. Brain Res. 2014 Oct 24;1586:83-9. 4. Watcharotayangul J, et al. Post-ischemic vascular adhesion protein-1 inhibition provides neuroprotection in a rat temporary middle cerebral artery occlusion model. J Neurochem. 2012 Nov;123 Suppl 2:116-24.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

LJP-1586 HCl 955037-42-0 Others LJP-1586 hydrochloride inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.