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LJP-1586 HCl

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Catalog No. T8857Cas No. 955037-42-0

Alias LJP-1586 hydrochloride, LJP-1586, LJP1586, LJP 1586

LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).

LJP-1586 HCl

😃Good

Purity: 99.20%

Catalog No. T8857Alias LJP-1586 hydrochloride, LJP-1586, LJP1586, LJP 1586Cas No. 955037-42-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$82	In Stock	In Stock
5 mg	$188	In Stock	In Stock
10 mg	$283	In Stock	In Stock
25 mg	$418	In Stock	In Stock
50 mg	$609	In Stock	In Stock
100 mg	$819	In Stock	In Stock
200 mg	$1,090	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.20%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).
Synonyms	LJP-1586 hydrochloride, LJP-1586, LJP1586, LJP 1586

Chemical Properties

Molecular Weight	231.69
Formula	C₁₁H₁₅ClFNO
Cas No.	955037-42-0
Smiles	C(/C(=C/F)/CN)C1=CC=C(OC)C=C1.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40 mg/mL (172.64 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	4.3161 mL	21.5806 mL	43.1611 mL	215.8056 mL
5 mM	0.8632 mL	4.3161 mL	8.6322 mL	43.1611 mL
10 mM	0.4316 mL	2.1581 mL	4.3161 mL	21.5806 mL
20 mM	0.2158 mL	1.0790 mL	2.1581 mL	10.7903 mL
50 mM	0.0863 mL	0.4316 mL	0.8632 mL	4.3161 mL
100 mM	0.0432 mL	0.2158 mL	0.4316 mL	2.1581 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc