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Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30)
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Catalog No. TMAY-01537
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F. Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) can be used in WB,ELISA.
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30)
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30)
😃Good
Catalog No. TMAY-01537
Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F. Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | 89 € | 7-10 days | |
| 100 μL | 277 € | 7-10 days |
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| Description | Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F. Anti-Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein/RSV-F Antibody (1M30) can be used in WB,ELISA. |
| Ig Type | Monoclonal mouse IgG1 |
| Clone | 1M30 |
| Verified Activity | Anti-RSV (A2) RSV-F mouse monoclonal antibody at 1:1000 dilution. -Lane A: RSV post-F Protein (10ng) -Lane B: RSV pre-F Protein (10ng) -Lane C: RSV-preF Protein (10ng) -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:1000-1:5000; ELISA: 1:1000-1:2000; ELISA(Cap): 1 mg/mL |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F (TMPY-01078; P03420.1; Met1-Thr529). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. The G protein mediates attachment of the virus to cell surface receptors, while the F protein promotes fusion of the viral and cellular membranes, allowing entry of the virus ribonucleoprotein into the cell cytoplasm. The fusion (F) protein of RSV is synthesized as a nonfusogenic precursor protein (F), which during its migration to the cell surface is activated by cleavage into the disulfide-linked F1 and F2 subunits. This fusion is pH independent and occurs directly at the outer cell membrane, and the F2 subunit was identifed as the major determinant of RSV host cell specificity. The trimer of F1-F2 interacts with glycoprotein G at the virion surface. Upon binding of G to heparan sulfate, the hydrophobic fusion peptide is unmasked and induces the fusion between host cell and virion membranes. Notably, RSV fusion protein is unique in that it is able to interact directly with heparan sulfate and therefore is sufficient for virus infection. Furthermore, the fusion protein is also able to trigger p53-dependent apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human respiratory syncytial virus (RSV) (A2) Fusion glycoprotein / RSV-F Protein (TMPY-01078) |
| Antigen Species | RSV |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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