GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-04265

GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.

GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-04265

GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$55	7-10 days	7-10 days
10 μg	$87	7-10 days	7-10 days
20 μg	$142	7-10 days	7-10 days
50 μg	$277	7-10 days	7-10 days
100 μg	$535	7-10 days	7-10 days
200 μg	$833	7-10 days	7-10 days
500 μg	$1,720	7-10 days	7-10 days
1 mg	$3,790	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Immobilized Human GITR Ligand Trimer, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 0.44 μg/ml determined by ELISA.
Description	GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9Y5U5-1
Synonyms	tumor necrosis factor receptor superfamily, member 18,GITR-D,GITR,CD357,AITR
Construction	Gln26-Glu161
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	41.3 kDa (Predicted); 45-55 kDa (Due to glycosylation)
Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.