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PD 117519

Name: PD 117519
Brand: TargetMol
SKU: T7509
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7509Cas No. 96392-15-3

Alias CI947

PD 117519 (CI947) is an agonist of the adenosine receptor.

PD 117519

🥰Excellent

Purity: 99.98%

Catalog No. T7509Alias CI947Cas No. 96392-15-3

PD 117519 (CI947) is an agonist of the adenosine receptor.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	In Stock	In Stock
5 mg	$50	In Stock	In Stock
10 mg	$83	In Stock	In Stock
25 mg	$148	In Stock	In Stock
50 mg	$271	In Stock	In Stock
100 mg	$397	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$55	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	PD 117519 (CI947) is an agonist of the adenosine receptor.
In vivo	PD 117519?selectively binds to adenosine A2 receptors (IC50 = 30 μM) over A1 receptors (IC50 = 810 μM) in rat brain membranes.?PD 117519 increases heart rate and decreases systolic blood pressure in normotensive dogs when administered at doses of 2 or 10 mg/kg[1].
Synonyms	CI947

Chemical Properties

Molecular Weight	383.4
Formula	C₁₉H₂₁N₅O₄
Cas No.	96392-15-3
Smiles	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3Cc4ccccc4C3)ncnc12
Relative Density.	1.71g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (260.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6082 mL	13.0412 mL	26.0824 mL	130.4121 mL
5 mM	0.5216 mL	2.6082 mL	5.2165 mL	26.0824 mL
10 mM	0.2608 mL	1.3041 mL	2.6082 mL	13.0412 mL
20 mM	0.1304 mL	0.6521 mL	1.3041 mL	6.5206 mL
50 mM	0.0522 mL	0.2608 mL	0.5216 mL	2.6082 mL
100 mM	0.0261 mL	0.1304 mL	0.2608 mL	1.3041 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc