Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 5 days | $ 32.00 | |
25 mg | 5 days | $ 48.00 |
Description | FmocNH-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | FmocNH-PEG4-t-butyl ester |
Molecular Weight | 543.657 |
Formula | C30H41NO8 |
CAS No. | 2148295-94-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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