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FMoc-Val-Cit-PAB-PNP

Name: FMoc-Val-Cit-PAB-PNP
Brand: TargetMol
SKU: T7767
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7767Cas No. 863971-53-3

Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC).

FMoc-Val-Cit-PAB-PNP

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Purity: 98.45%

Catalog No. T7767Cas No. 863971-53-3

Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC).

Pack Size	Price	Availability	Quantity
100 mg	$42	In Stock

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Batch Information

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Purity:98.45%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC).

Chemical Properties

Molecular Weight	766.8
Formula	C₄₀H₄₂N₆O₁₀
Cas No.	863971-53-3
Smiles	O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O)=O
Relative Density.	1.335 g/cm3 (Predicted)
Sequence Short	Fmoc-V-Cit-PAB-PNP

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (52.16 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3041 mL	6.5206 mL	13.0412 mL	65.2061 mL
5 mM	0.2608 mL	1.3041 mL	2.6082 mL	13.0412 mL
10 mM	0.1304 mL	0.6521 mL	1.3041 mL	6.5206 mL
20 mM	0.0652 mL	0.3260 mL	0.6521 mL	3.2603 mL
50 mM	0.0261 mL	0.1304 mL	0.2608 mL	1.3041 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc