DFF45 Protein, Human, Recombinant (His)

Name: DFF45 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00483
Rating: 4.5 (1 reviews)

(Synonyms: Inhibitor of CAD, ICAD, H13, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFFA, DFF-45, DFF45, DFF1) Copy Product Info

Synonyms: Inhibitor of CAD, ICAD, H13, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFFA, DFF-45, DFF45, DFF1

Catalog No. TMPJ-00483 Copy Product Info

DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

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Pack Size	Price	USA Stock	Global Stock
5 μg	$72	35 days	35 days
10 μg	$116	35 days	35 days
20 μg	$176	35 days	35 days
50 μg	$310	35 days	35 days
100 μg	$532	35 days	35 days
200 μg	$919	35 days	35 days
500 μg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAH07721.1
Amino Acid	Met1-Thr331
Construction	Met1-Thr331
Protein Purity	Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	Inhibitor of CAD, ICAD, H13, DNA Fragmentation Factor Subunit α, DNA Fragmentation Factor Subunit Alpha, DNA Fragmentation Factor 45 kDa Subunit, DFFA, DFF-45, DFF45, DFF1
Research Background

Chemical Properties

Molecular Weight

40-50 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

H-13H 13DFF-1DFF 45DFF 1

Related Tags: DFF45 Protein, Human, Recombinant (His) chemical structure | DFF45 Protein, Human, Recombinant (His) molecular weight