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AMP-PNP tetralithium

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Catalog No. T37733Cas No. 72957-42-7
Alias Adenylyl-imidodiphosphate tetralithium

AMP-PNP tetralithium（Adenylyl-imidodiphosphate tetralithium） is a non-hydrolyzable ATP analog that fully occupies ATP-binding sites without undergoing enzymatic hydrolysis, thereby providing stable and controlled experimental conditions for dissecting ATP-dependent biological processes. AMP-PNP is widely used to investigate enzyme activity, kinase regulation, DNA and RNA metabolism, ion channel function, and protein complex assembly in biochemical and structural biology studies.

AMP-PNP tetralithium

AMP-PNP tetralithium

😃Good
Catalog No. T37733Alias Adenylyl-imidodiphosphate tetralithiumCas No. 72957-42-7
AMP-PNP tetralithium（Adenylyl-imidodiphosphate tetralithium） is a non-hydrolyzable ATP analog that fully occupies ATP-binding sites without undergoing enzymatic hydrolysis, thereby providing stable and controlled experimental conditions for dissecting ATP-dependent biological processes. AMP-PNP is widely used to investigate enzyme activity, kinase regulation, DNA and RNA metabolism, ion channel function, and protein complex assembly in biochemical and structural biology studies.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$88335 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Description
AMP-PNP tetralithium（Adenylyl-imidodiphosphate tetralithium） is a non-hydrolyzable ATP analog that fully occupies ATP-binding sites without undergoing enzymatic hydrolysis, thereby providing stable and controlled experimental conditions for dissecting ATP-dependent biological processes. AMP-PNP is widely used to investigate enzyme activity, kinase regulation, DNA and RNA metabolism, ion channel function, and protein complex assembly in biochemical and structural biology studies.
SynonymsAdenylyl-imidodiphosphate tetralithium
Chemical Properties
Molecular Weight529.93
FormulaC10H13Li4N6O12P3
Cas No.72957-42-7
SmilesO[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(NP([O-])([O-])=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Li+].[Li+].[Li+].[Li+]
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20 mg/mL (37.74 mM), onication and heating are recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.8870 mL9.4352 mL18.8704 mL94.3521 mL
5 mM0.3774 mL1.8870 mL3.7741 mL18.8704 mL
10 mM0.1887 mL0.9435 mL1.8870 mL9.4352 mL
20 mM0.0944 mL0.4718 mL0.9435 mL4.7176 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

AMP-PNP tetralithiumAMPPNP tetralithiumAMP-PNPAMP PNP tetralithium
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