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Anti-PDK1 Polyclonal Antibody
(Synonyms: pyruvate dehydrogenase kinase, isozyme 1, PDHK1) Copy Product Info
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Synonyms: pyruvate dehydrogenase kinase, isozyme 1, PDHK1
Catalog No. TMAB-01357 Copy Product Info
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Anti-PDK1 Polyclonal Antibody is a Rabbit antibody targeting PDK1. Anti-PDK1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-PDK1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PDK1 Polyclonal Antibody is a Rabbit antibody targeting PDK1. Anti-PDK1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | pyruvate dehydrogenase kinase, isozyme 1, PDHK1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. |
| Tissue Specificity | Expressed predominantly in the heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013] |
| Immunogen | KLH conjugated synthetic peptide: human PDK1 |
| Antigen Species | Human |
| Gene Name | PDK1 |
| Gene ID | |
| Protein Name | [Pyruvate dehydrogenase(acetyl-transferring)] kinase isozyme 1, mitochondrial |
| Uniprot ID | |
| Biology Area | Cellular metabolic process,Integration of energy metabolism,Metabolism of carbohydrates,Carbohydrate metabolism,Energy Metabolism,Integration of energy,Energy Metabolism |
| Function | Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. |
| Molecular Weight | Theoretical: 45 kDa. Actual: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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