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Pardoprunox hydrochloride

Name: Pardoprunox hydrochloride
Brand: TargetMol
SKU: T3431
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3431Cas No. 269718-83-4

Alias SLV-308 hydrochloride, DU-126891 hydrochloride

Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.

Pardoprunox hydrochloride

🥰Excellent

Purity: 99.13%

Catalog No. T3431Alias SLV-308 hydrochloride, DU-126891 hydrochlorideCas No. 269718-83-4

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$44	In Stock
10 mg	$73	In Stock
25 mg	$123	In Stock
50 mg	$198	In Stock
100 mg	$372	In Stock

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Purity:99.13%

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Product Introduction

Bioactivity

Description	Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
Targets&IC50	5-HT1A receptor:8.5 (pKi), D2 receptor:8.1(pKi ), D3 receptor:8.6(pKi)
Synonyms	SLV-308 hydrochloride, DU-126891 hydrochloride

Chemical Properties

Molecular Weight	269.73
Formula	C₁₂H₁₆ClN₃O₂
Cas No.	269718-83-4
Smiles	Cl.CN1CCN(CC1)c1cccc2[nH]c(=O)oc12
Relative Density.	no data available

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: < 1 mg/mL (insoluble or slightly soluble) H2O: < 0.1 mg/mL (insoluble)

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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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