Ephrin A3/EFNA3 Protein, Human, Recombinant

Name: Ephrin A3/EFNA3 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-00791
Rating: 4.5 (1 reviews)

(Synonyms: LERK3, EPLG3, ephrin-A3, Ehk1-L, EFL2) Copy Product Info

Synonyms: LERK3, EPLG3, ephrin-A3, Ehk1-L, EFL2

Catalog No. TMPY-00791 Copy Product Info

Ephrin A3/EFNA3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22 kDa and the accession number is P52797-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$87	7-10 days	7-10 days
20 µg	$142	7-10 days	7-10 days
50 µg	$277	7-10 days	7-10 days
100 µg	$535	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to bind biotinylated mouse EPHA6-Fc in a functional ELISA.
Description	Ephrin A3/EFNA3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22 kDa and the accession number is P52797-1.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P52797-1
Construction	A DNA sequence encoding the human EphrinA3 (NP_004943.1) (Met 1-Ser 213) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified. Predicted N terminal: Gln 23
Protein Purity	> 70 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 100 mM NaCl, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	LERK3, EPLG3, ephrin-A3, Ehk1-L, EFL2
Research Background	Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A3 and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: Ephrin-A3 ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A3 expressed on astrocytes activates EphA4 on the post-synaptic neuron and restricts the growth of dendritic spines through multiple pathways.

Chemical Properties

Molecular Weight

22 kDa (predicted); 35-40 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.