Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to maintain the integrity of the extracellular matrix.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 184.00 | |
50 μg | 5 days | $ 545.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,970.00 |
Description | Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to maintain the integrity of the extracellular matrix. |
Species | Human |
Expression System | Human Cells |
Tag | C-6His |
Accession Number | Q96P44 |
Synonyms | collagen, type XXI, alpha 1, COL21A1, FLJ44623, DKFZp564B052, collagen alpha-1(XXI) chain, collagen, type XXI, α1, MGC26619, dJ682J15.1, COLA1L, α 1 type XXI collagen, dJ708F5.1, FLJ39125, collagen α-1(XXI) chain, FP633, alpha 1 type XXI collagen |
Amino Acid | Glu23-Tyr957 |
Construction | Recombinant Human Collagen Alpha-1(XXI) Chain is produced by our Mammalian expression system and the target gene encoding Glu23-Tyr957 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 115-125&220 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to maintain the integrity of the extracellular matrix. |
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Please read the User Guide of Recombinant Proteins for more specific information.
COL21A1 Protein, Human, Recombinant (His) collagen, type XXI, alpha 1 COL21A1 MGC-26619 FLJ 39125 FLJ44623 DKFZp564B052 FP 633 collagen, type XXI, a 1 a 1 type XXI collagen FLJ-39125 collagen alpha-1(XXI) chain collagen, type XXI, α1 MGC26619 FLJ 44623 dJ682J15.1 MGC 26619 COLA1L DKFZp564B 052 FP-633 collagen a-1(XXI) chain α 1 type XXI collagen dJ708F5.1 FLJ39125 collagen α-1(XXI) chain FLJ-44623 collagen, type XXI, α 1 FP633 DKFZp564B-052 alpha 1 type XXI collagen recombinant recombinant-proteins proteins protein