Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Ceftobiprole

Copy Product Info
😃Good
Catalog No. TQ0077Cas No. 209467-52-7
Alias Ro 63-9141, BAL 9141

Ceftobiprole (Ro 63-9141) is a β-lactam antibacterial agent that exhibits potent bactericidal activity by binding to PBPs, inhibiting transpeptidation and formation of bacterial cell walls, leading to cell lysis and death, with a MIC90 value of 2 μg/mL against methicillin-resistant Staphylococcus aureus.

Ceftobiprole

Ceftobiprole

Copy Product Info
😃Good
Purity: 95%
Catalog No. TQ0077Alias Ro 63-9141, BAL 9141Cas No. 209467-52-7
Ceftobiprole (Ro 63-9141) is a β-lactam antibacterial agent that exhibits potent bactericidal activity by binding to PBPs, inhibiting transpeptidation and formation of bacterial cell walls, leading to cell lysis and death, with a MIC90 value of 2 μg/mL against methicillin-resistant Staphylococcus aureus.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$133In StockIn Stock
5 mg$297In StockIn Stock
10 mg$459In Stock-
25 mg$742InquiryInquiry
50 mg$987InquiryInquiry
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:95%
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

Product Introduction

Bioactivity
Description
Ceftobiprole (Ro 63-9141) is a β-lactam antibacterial agent that exhibits potent bactericidal activity by binding to PBPs, inhibiting transpeptidation and formation of bacterial cell walls, leading to cell lysis and death, with a MIC90 value of 2 μg/mL against methicillin-resistant Staphylococcus aureus.
Targets&IC50
MRSA:2 μg/mL (MIC90)
In vitro
Ceftobiprole (Ro 63-9141) has demonstrated activity against clinically important Gram-positive bacteria, including penicillin-resistant Streptococcus pneumoniae (PRSP), methicillin-resistant Staphylococcus aureus (MRSA), and Enterobacter faecalis with MIC90 values ​​of 0.25, 2, and 2 mcg/mL, respectively; ceftobiprole has also shown in vitro activity against several clinical isolates of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), vancomycin-intermediate Staphylococcus aureus (VISA), and vancomycin-resistant Staphylococcus aureus (VRSA) with a minimum inhibitory concentration (MIC) of 2 mcg/mL.
SynonymsRo 63-9141, BAL 9141
Chemical Properties
Molecular Weight534.57
FormulaC20H22N8O6S2
Cas No.209467-52-7
Smiles[H][C@]12SCC(\C=C3/CCN([C@@H]4CCNC4)C3=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/O)\c1nsc(N)n1)C(O)=O
Relative Density.2 g/cm3
Storage & Solubility Information
StorageThe compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: < 1 mg/mL (insoluble or slightly soluble), Sonication is recommended. The compound is unstable in solution. Please use soon.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Ceftobiprole | purchase Ceftobiprole | Ceftobiprole cost | order Ceftobiprole | Ceftobiprole chemical structure | Ceftobiprole in vitro | Ceftobiprole formula | Ceftobiprole molecular weight