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Ipamorelin 2 Pivalic acid
🥰Excellent
Catalog No. T7809L
Alias NNC-26-0161
Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats.
Ipamorelin 2 Pivalic acid
🥰Excellent
Catalog No. T7809LAlias NNC-26-0161
Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $54 | In Stock | In Stock | |
| 2 mg | $76 | In Stock | In Stock | |
| 5 mg | $117 | In Stock | In Stock | |
| 10 mg | $153 | In Stock | In Stock | |
| 25 mg | $277 | In Stock | In Stock | |
| 50 mg | $415 | In Stock | In Stock | |
| 100 mg | $617 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:>99.99%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ipamorelin 2 Pivalic acid (NNC-26-0161) is a growth-hormone-releasing peptide, induces longitudinal bone growth in rats. |
| In vitro | In vitro, ipamorelin released GH from primary rat pituitary cells with a potency and efficacy similar to GHRP-6 (ECs) = 1.3+/-0.4nmol/l and Emax = 85+/-5% vs 2.2+/-0.3nmol/l and 100%).?A pharmacological profiling using GHRP and growth hormone-releasing hormone (GHRH) antagonists clearly demonstrated that ipamorelin, like GHRP-6, stimulates GH release via a GHRP-like receptor[1] |
| In vivo | In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml).?In conscious swine, ipamorelin released GH with an ED50 = 2.3+/-0.03 nmol/kg and an Emax = 65+/-0.2 ng GH/ml plasma.?Again, this was very similar to GHRP-6 (ED50 = 3.9+/-1.4 nmol/kg and Emax = 74+/-7ng GH/ml plasma)[1]. |
| Synonyms | NNC-26-0161 |
| Molecular Weight | 916.12 |
| Formula | C38H49N9O5.2C5H10O2 |
| Smiles | CC(C)(C)C(O)=O.CC(C)(C)C(O)=O.CC(C)(N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O |
| Relative Density. | no data available |
| Sequence | H-Aib-His-D-2Nal-D-Phe-Lys-NH2 |
| Sequence Short | XHXFK |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 10 mM, Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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