BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

Catalog No. TMPY-01136

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is P12643.

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

Catalog No. TMPY-01136

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is P12643.

Pack Size	Price	Availability
5 μg	$98	7-10 days
10 μg	$166	7-10 days
20 μg	$275	In Stock
50 μg	$393	7-10 days
100 μg	$539	In Stock
200 μg	$945	7-10 days
500 μg	$1,990	7-10 days
1 mg	$3,520	7-10 days

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Product Information

Biological Activity	Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.1-0.5 μg/mL.
Description	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is P12643.
Species	Human,Mouse,Rat,Rhesus,Canine
Expression System	E. coli
Tag	Tag Free
Accession Number	P12643
Synonyms	bone morphogenetic protein 2
Construction	A DNA sequence encoding the mature form of human / mouse / rat / rhesus / canine BMP2 (NP_001191.1) (Gln283-Arg396) was expressed with an initial Met. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical. Predicted N terminal: Met
Protein Purity	> 95% as determined by SDS-PAGE
Molecular Weight	13 kDa (predicted); 14 & 27 kDa (reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 30% ACN, 1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.