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HIVgp120 (318-327) is a short sequence (rgpgrafvti) from the envelope peptide of the HIV-1 IIIB strain, corresponding to the conserved C-terminal region of the glycoprotein. It is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIVgp120 (318-327) lacks the A2 anchor residues needed for epitope-specific CTL recognition but possesses structural features that allow mixed A2 binding.

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| Description | HIVgp120 (318-327) is a short sequence (rgpgrafvti) from the envelope peptide of the HIV-1 IIIB strain, corresponding to the conserved C-terminal region of the glycoprotein. It is part of the HIV vaccine V3 peptide epitope, also known as the I10 peptide. However, HIVgp120 (318-327) lacks the A2 anchor residues needed for epitope-specific CTL recognition but possesses structural features that allow mixed A2 binding. |
| In vitro | HIV gp120 (318-327) (0.5 μM) reduces the CTL response in JA2 cells that express the 7DV3 mutant [1]. |
| Molecular Weight | 1073.25 |
| Formula | C48H80N16O12 |
| Cas No. | 147841-68-7 |
| Smiles | C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)=O)C)=O)CCCNC(=N)N)=O)(=O)[C@H]2N(C(CNC([C@H](CCCNC(=N)N)N)=O)=O)CCC2 |
| Sequence | Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile |
| Sequence Short | RGPGRAFVTI |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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