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Anti-Phospho-p56 Dok-2 (Tyr299) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p56 Dok-2 (Tyr299). Anti-Phospho-p56 Dok-2 (Tyr299) Polyclonal Antibody can be used in WB,IHC,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-p56 Dok-2 (Tyr299) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p56 Dok-2 (Tyr299). Anti-Phospho-p56 Dok-2 (Tyr299) Polyclonal Antibody can be used in WB,IHC,IF. |
Alias | p-p56 Dok-2 (Y299), p-p56 Dok-2 (Tyr299), p56 Dok-2 (p-Y299), p56 Dok-2 (p-Tyr299) |
Ig Type | IgG |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of extracts from Jurkat cells untreated or treated with insulin using p56Dok-2 (Phospho-Tyr299) Antibody TMAC-03005. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p56Dok-2 (Phospho-Tyr299) Antibody TMAC-03005 (left) or the same antibody preincubated with blocking peptide (right). 3. Immunofluorescence staining of methanol-fixed Hela cells using p56Dok-2 (Phospho-Tyr299) Antibody TMAC-03005. 4. Western blot analysis of extracts from JK cells, treated with G-CSF or calf intestinal phosphatase (CIP), using p56Dok-2 (Phospho-Tyr299) Antibody TMAC-03005. |
Application | |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Appearance | Liquid |
Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2 |
Antigen Species | human |
Uniprot ID |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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