keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pro8-Oxytocin, a modified oxytocin (OXT) ligand, elicits more potent and efficacious responses at primate OXTR and induces stronger behavioral effects compared to the standard mammalian OXT ligand (Leu8-Oxytocin). It demonstrates lower efficacy than Vasopressin (AVP) at human AVPR1a, yet shows a higher efficacious response at marmoset AVPR1a [1].
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Description | Pro8-Oxytocin, a modified oxytocin (OXT) ligand, elicits more potent and efficacious responses at primate OXTR and induces stronger behavioral effects compared to the standard mammalian OXT ligand (Leu8-Oxytocin). It demonstrates lower efficacy than Vasopressin (AVP) at human AVPR1a, yet shows a higher efficacious response at marmoset AVPR1a [1]. |
In vitro | Pro8-Oxytocin, at concentrations ranging from 1 nM to 10 μM, is capable of inducing calcium mobilization in CHO cells expressing the AVPR1a receptor [1]. |
In vivo | Pro8-Oxytocin exhibits higher binding affinity for the primate oxytocin receptor (OXTR) than Leu8-Oxytocin, particularly in primates expressing Pro8-OXT and Leu8-OXT, resulting in a more potent calcium signaling response [1]. |
Molecular Weight | 991.14 |
Formula | C42H62N12O12S2 |
CAS No. | 24327-19-3 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Pro8-Oxytocin 24327-19-3 Endocrinology/Hormones GPCR/G Protein Oxytocin Receptor inhibitor inhibit