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TargetMol | Compound Library

Serotonin Receptor-Targeted Compound Library

Catalog No. L2800

Serotonin or 5-hydroxytryptamine (5-HT Receptor) is a monoamine neurotransmitter, derivative from the amino acid tryptophan, and mainly located in the enterochromaffin cells in the GI tract and central nervous system (CNS). It has a popular image as a contributor to feelings of well-being and happiness, though its actual biological function is complex and multifaceted, modulating cognition, reward, learning, memory, and numerous physiological processes. Serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They can be divided into 7 families of G protein-coupled receptors except for the 5-HT3 receptor, a ligand-gated ion channel, which activate an intracellular second messenger cascade to produce an excitatory or inhibitory response. They mediate both excitatory and inhibitory neurotransmission, influencing various biological and neurological processes. The serotonin receptors are the target of a variety of pharmaceutical and recreational drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens. The Serotonin (5-HT) Compound Library by TargetMol, collecting 424 small chemicals targeting serotonin receptors, can be used for high throughput screening and high content screening, and drug discovery in neurological disorders.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2800

Serotonin Receptor-Targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 424 compounds targeting serotonin receptors for high throughput screening and high content screening;
  • Targets include serotonin receptors: 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT6, 5-HT7, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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5-HT Receptor
Dopamine Receptor
Adrenergic Receptor
Histamine Receptor
Serotonin Transporter
AChR
Norepinephrine
Autophagy
Potassium Channel
Apoptosis
Endogenous Metabolite
Antibacterial
Sodium Channel
Sigma receptor
Drug Metabolite
Calcium Channel
Opioid Receptor
MAO
Reactive Oxygen Species
Cytochromes P450
P2X Receptor
Cholinesterase (ChE)
Hydroxylase
EGFR
GABA Receptor
Transferase
PKA
GluR
Melatonin Receptor
NO Synthase
Trk receptor
GPCR
Parasite
PKC
TRP/TRPV Channel
CaMK
Beta Amyloid
Anti-infection
Caspase
Influenza Virus
Melanin-concentrating Hormone Receptor (MCHR)
p38 MAPK
Mitophagy
Glucosidase
TGF-beta/Smad
SARS-CoV
Phospholipase
Virus Protease
iGluR
Monoamine Transporter
CCR
NOS
Phosphatase
Leukotriene Receptor
PDE
P-gp
Prostaglandin Receptor
PAFR
ROS
IL Receptor
Ferroptosis
Adenosine Receptor
Na+/Ca2+ Exchanger
DYRK
PARP
ERK
Bcl-2 Family
GST
Antibiotic
Dehydrogenase
OCT
GRK
MT Receptor
Stearoyl-CoA Desaturase (SCD)
COX
transporter
Monoamine Oxidase
Histone Methyltransferase
MRP
GlyT
FGFR

Keywords