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GMPR Protein, Human, Recombinant (His)

(Synonyms: guanosine monophosphate reductase, GMPR1) Copy Product Info

Synonyms: guanosine monophosphate reductase, GMPR1

Catalog No. TMPY-03617 Copy Product Info
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
GMPR Protein, Human, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1297-10 days7-10 days
20 µg$2087-10 days7-10 days
50 µg$4197-10 days7-10 days
100 µg$8127-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it.
Description
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Species
Human
Expression System
HEK293 Cells
TagN-His
Accession NumberP36959
ConstructionA DNA sequence encoding the human GMPR (NP_006868.3)(Met1-Ser345) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity
> 95% as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as sterile 50 mM Tris, 150 mM NaCl, 40% Glycerol, 1 mM DTT, pH 8.0.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymsguanosine monophosphate reductase, GMPR1
Research Background
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Chemical Properties
Molecular Weight38.5 kDa (predicted); 40 kDa (reducing conditions)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: GMPR Protein, Human, Recombinant (His) chemical structure | GMPR Protein, Human, Recombinant (His) molecular weight