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Sultopride hydrochloride
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Catalog No. T7180Cas No. 23694-17-9
Alias LIN-1418 hydrochloride
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist for dopamine D2 and D3 receptors.
Sultopride hydrochloride
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Purity: 99.97%
Catalog No. T7180Alias LIN-1418 hydrochlorideCas No. 23694-17-9
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist for dopamine D2 and D3 receptors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $30 | In Stock | In Stock | |
| 5 mg | $64 | In Stock | In Stock | |
| 10 mg | $98 | In Stock | In Stock | |
| 25 mg | $197 | In Stock | In Stock | |
| 50 mg | $297 | In Stock | In Stock | |
| 100 mg | $446 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $71 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
Appearance:Solid
Color:White
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist for dopamine D2 and D3 receptors. |
| In vivo | Sultopride and sulpiride are both chemically similar benzamide derivatives and selective antagonists of dopamine D2 receptors.?However, these drugs differ in clinical properties.?We compared the effects of sultopride and sulpiride on dopamine turnover in rats following the administration of these drugs alone or in combination with apomorphine.?The administration of sultopride or sulpiride markedly accelerated dopamine turnover in the rat brain.?The increase in the level of dopamine metabolites in the striatum was more marked in the sultopride-treated rats.?Sulpiride affected the limbic dopamine receptors preferentially, whereas sultopride affected the striatal and the limbic dopamine receptors equally.?A low dose of apomorphine induced a reduction in the concentration of dopamine metabolites in the striatum and the nucleus accumbens by approximately 55%, but not in the medial prefrontal cortex.?Sultopride was more effective in preventing an apomorphine-induced reduction in dopamine metabolite levels. |
| Synonyms | LIN-1418 hydrochloride |
| Molecular Weight | 390.93 |
| Formula | C17H27ClN2O4S |
| Cas No. | 23694-17-9 |
| Smiles | Cl.CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC |
| Relative Density. | 1.16g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (127.9 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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