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UDP-GalNAc disodium

Name: UDP-GalNAc disodium
Brand: TargetMol
SKU: T73809
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: UDP-N-acetyl-D-galactosamine disodium) Copy Product Info

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Synonyms: UDP-N-acetyl-D-galactosamine disodium

Catalog No. T73809 Copy Product Info

Purity: 99.99%

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UDP-GalNAc disodium is a key sugar nucleotide and serves as the catalytic substrate of EpsC115 (a truncated mutant protein of extracellular polymeric substance (EPS) with amino acids 1–115 at the N-terminus). It is a universal glycosyl donor for various N-acetylgalactosaminyltransferases, mediating the transfer of GalNAc groups from nucleotide sugars to carbohydrate or polypeptide receptors and providing essential glycosyl precursors for various glycosylation modification reactions. At present, UDP-GalNAc disodium has been widely applied in mechanism research of colorectal cancer, breast cancer and other tumors.

Cas No. 108320-87-2

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Pack Size	Price	USA Stock	Global Stock
1 mg	$64	-	In Stock
5 mg	$129	-	In Stock
10 mg	$197	-	In Stock
25 mg	$355	-	In Stock
50 mg	$533	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.99%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	UDP-GalNAc disodium is a key sugar nucleotide and serves as the catalytic substrate of EpsC115 (a truncated mutant protein of extracellular polymeric substance (EPS) with amino acids 1–115 at the N-terminus). It is a universal glycosyl donor for various N-acetylgalactosaminyltransferases, mediating the transfer of GalNAc groups from nucleotide sugars to carbohydrate or polypeptide receptors and providing essential glycosyl precursors for various glycosylation modification reactions. At present, UDP-GalNAc disodium has been widely applied in mechanism research of colorectal cancer, breast cancer and other tumors.
In vitro	Methods: Using UDP-GalNAc disodium at a final concentration of 25 μM as the substrate, purified ppGalNAc-T2 and ppGalNAc-T3 proteins were applied to perform in vitro glycosylation assays. Results: UDP-GalNAc disodium at 25 μM can serve as a reaction substrate for the in vitro functional verification of glycosylation activity of ppGalNAc-T2 and ppGalNAc-T3 [3].
Synonyms	UDP-N-acetyl-D-galactosamine disodium

Chemical Properties

Molecular Weight	651.32
Formula	C₁₇H₂₅N₃Na₂O₁₇P₂
Cas No.	108320-87-2
Smiles	O[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]([C@H]1O)COP(OP(O[C@@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)([O-])=O)([O-])=O.[Na+].[Na+]

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (153.53 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.5353 mL	7.6767 mL	15.3534 mL	76.7672 mL
5 mM	0.3071 mL	1.5353 mL	3.0707 mL	15.3534 mL
10 mM	0.1535 mL	0.7677 mL	1.5353 mL	7.6767 mL
20 mM	0.0768 mL	0.3838 mL	0.7677 mL	3.8384 mL
50 mM	0.0307 mL	0.1535 mL	0.3071 mL	1.5353 mL
100 mM	0.0154 mL	0.0768 mL	0.1535 mL	0.7677 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: UDP-GalNAc disodium chemical structure | UDP-GalNAc disodium in vitro | UDP-GalNAc disodium formula | UDP-GalNAc disodium molecular weight