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Anti-TROP-2 Antibody-PE (1P681) (Synonyms: tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2...)

Name: Anti-TROP-2 Antibody-PE (1P681)
Brand: TargetMol
SKU: TMAY-00816P
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00816P Copy Product Info

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Anti-TROP-2 Antibody-PE (1P681) is a PE-conjugated Rabbit antibody targeting TROP-2. Anti-TROP-2 Antibody-PE (1P681) can be used in FCM.

Anti-TROP-2 Antibody-PE (1P681)

Copy Product Info

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Catalog No. TMAY-00816P

Synonyms tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1

Anti-TROP-2 Antibody-PE (1P681) is a PE-conjugated Rabbit antibody targeting TROP-2. Anti-TROP-2 Antibody-PE (1P681) can be used in FCM.

Anti-TROP-2 Antibody-PE
(1P681)

Pack Size	Price	USA Stock	Global Stock	Quantity
25 T	$105	7-10 days	7-10 days
100 T	$327	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-TROP-2 Antibody-PE (1P681) is a PE-conjugated Rabbit antibody targeting TROP-2. Anti-TROP-2 Antibody-PE (1P681) can be used in FCM.
Synonyms	tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1
Ig Type	Rabbit IgG
Clone	1P681
Reactivity	Human
Specificity	Human TROP-2
Verified Activity	Flow cytometric analysis of anti-Human TROP2 on MCF-7 cells.
Application	FCM
Recommended Dose	5 μl/Test, 0.1 mg/ml
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human TROP2 / TACSTD2 (rh TROP2 / TACSTD2; TMPY-01262; NP_002344.2; Met1-Thr274) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Purification	Protein A
Appearance	Liquid
Formulation	PBS solution containing 0.5% BSA and 0.03%ProClin300
Research Background	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.

Related Conjugates and Formulations

Conjucates	PE
Others Formats	Unconjugated/APC/FITC
Antibody Types Available	4

Antigen Details

Immunogen	Recombinant Protein: Human TROP2 / TACSTD2 protein (TMPY-01262)
Antigen Species	Human
Biology Area	Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
Transport	Shipping with blue ice.

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Keywords

TROP 2TACD-2TACD 2GP-50GP 50GA-7331GA 7331EGP 1

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