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Anti-PTPN14 Antibody (8D656)
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Catalog No. TMAC-03467
Alias Tyrosine-protein phosphatase non-receptor type 14, PTPN14, PTPD2, Protein-tyrosine phosphatase pez, PEZ
Anti-PTPN14 Antibody (8D656) is a Mouse antibody targeting PTPN14. Anti-PTPN14 Antibody (8D656) can be used in WB,ICC,IHC,FCM.
Anti-PTPN14 Antibody (8D656)
Anti-PTPN14 Antibody (8D656)
😃Good
Catalog No. TMAC-03467Alias Tyrosine-protein phosphatase non-receptor type 14, PTPN14, PTPD2, Protein-tyrosine phosphatase pez, PEZ
Anti-PTPN14 Antibody (8D656) is a Mouse antibody targeting PTPN14. Anti-PTPN14 Antibody (8D656) can be used in WB,ICC,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $426 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PTPN14 Antibody (8D656) is a Mouse antibody targeting PTPN14. Anti-PTPN14 Antibody (8D656) can be used in WB,ICC,IHC,FCM. |
| Synonyms | Tyrosine-protein phosphatase non-receptor type 14, PTPN14, PTPD2, Protein-tyrosine phosphatase pez, PEZ |
| Clone | 8D656 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of PTPN14 on human PTPN14 ecombinant protein using anti-PTPN14 antibody at 1/1,000 dilution. 2. Western blot analysis of PTPN14 on HEK293 (1) and PTPN14-hIgGFc transfected HEK293 (2) cell lysate using anti-PTPN14 antibody at 1/1,000 dilution. 3. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-PTPN14 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-PTPN14 antibody. Counter stained with hematoxylin. 5. ICC staining PTPN14 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of Hela cells with PTPN14 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 135 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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