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Anti-CYP17A1 Antibody (1U433)
(Synonyms: Steroid 17-alpha-monooxygenase, Steroid 17-alpha-hydroxylase/17,20 lyase, S17AH, Cytochrome P450-C17 (Cytochrome P450c17), Cytochrome P450 17A1, CYPXVII, CYP17A1, CYP17, 20 lyase, 17-alpha-hydroxyprogesterone aldolase) Copy Product Info
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Synonyms: Steroid 17-alpha-monooxygenase, Steroid 17-alpha-hydroxylase/17,20 lyase, S17AH, Cytochrome P450-C17 (Cytochrome P450c17), Cytochrome P450 17A1, CYPXVII, CYP17A1, CYP17, 20 lyase, 17-alpha-hydroxyprogesterone aldolase
Catalog No. TMAC-01069 Copy Product Info
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Anti-CYP17A1 Antibody (1U433) is a Rabbit antibody targeting CYP17A1. Anti-CYP17A1 Antibody (1U433) can be used in FCM,ICC,IF,IHC,WB.
Anti-CYP17A1 Antibody
(1U433)
(1U433)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-CYP17A1 Antibody (1U433) is a Rabbit antibody targeting CYP17A1. Anti-CYP17A1 Antibody (1U433) can be used in FCM,ICC,IF,IHC,WB. |
| Synonyms | Steroid 17-alpha-monooxygenase, Steroid 17-alpha-hydroxylase/17,20 lyase, S17AH, Cytochrome P450-C17 (Cytochrome P450c17), Cytochrome P450 17A1, CYPXVII, CYP17A1, CYP17, 20 lyase, 17-alpha-hydroxyprogesterone aldolase |
| Ig Type | IgG |
| Clone | 1U433 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies, such as CYP1A, CYP2A, CYP2C, CYP2D, CYP4A14, CYP7A, CYP7B, CYP8B, CYP11A, CYP17A1, CYPI9 and CYP27A, based on sequence similarities. CYP17A (17alpha-hydroxylase/17,20-lyase) is important for the conversion of pregnenolone and progesterone to dehydroepiandrosterone (DHEA) and androstenedione. In this process, it catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is crucial during sexual development, both during fetal development and during puberty, and is intracellularly regulated by cAMP levels. Defects in the CYP17A1 gene, which encodes for the protein, may cause adrenal hyperplasia type V (AH-V) which is characterized by hypokalemia and hypertension. Male patients affected by AH-V do not undergo normal sexual differentiation and develop female external genitalia and do not undergo pubertal develoment. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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