CHRDL1 Protein, Human, Recombinant (His)

Name: CHRDL1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01152
Rating: 4.5 (1 reviews)

(Synonyms: VOPT, Ventroptin, NRLN1, Neurogenesin-1, Neuralin-1, dA141H5.1, CRDL1, CHRDL1, Chordin-like 1, CHL) Copy Product Info

Synonyms: VOPT, Ventroptin, NRLN1, Neurogenesin-1, Neuralin-1, dA141H5.1, CRDL1, CHRDL1, Chordin-like 1, CHL

Catalog No. TMPK-01152 Copy Product Info

CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.

CHRDL1 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$61	7-10 days	7-10 days
10 μg	$96	7-10 days	7-10 days
20 μg	$156	7-10 days	7-10 days
50 μg	$297	7-10 days	7-10 days
100 μg	$511	7-10 days	7-10 days
200 μg	$925	7-10 days	7-10 days
500 μg	$2,030	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity


Description	CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	Q9BU40-6
Construction	Glu28-Cys456
Protein Purity	> 90% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl. Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in 4mM HCl. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	VOPT, Ventroptin, NRLN1, Neurogenesin-1, Neuralin-1, dA141H5.1, CRDL1, CHRDL1, Chordin-like 1, CHL
Research Background

Chemical Properties

Molecular Weight

50 kDa (predicted) same as Tris-Bis PAGE result.

Storage & Solubility Information

Storage

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NRLN-1NRLN 1CRDL-1CRDL 1CHRDL-1CHRDL 1

Related Tags: CHRDL1 Protein, Human, Recombinant (His) chemical structure | CHRDL1 Protein, Human, Recombinant (His) molecular weight