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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | HO-PEG-amine (MW 1000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system in cells. |
In vitro | PROTACs are composed of two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to a target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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