IFNGR2 Protein, Human, Recombinant

Name: IFNGR2 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPS-00052
Rating: 4.5 (1 reviews)

(Synonyms: IFNGT1, IFNGR2) Copy Product Info

Synonyms: IFNGT1, IFNGR2

Catalog No. TMPS-00052 Copy Product Info

IFNGR2 Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P38484.

Pack Size	Price	USA Stock	Global Stock
5 µg	$71	7-10 days	7-10 days
10 µg	$113	7-10 days	7-10 days
20 µg	$168	7-10 days	7-10 days
50 µg	$297	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	ED 50 < 0.1 μg/ml, measured in a cell cytotoxicity assay using HT-29 (HTB-38) cells in the presence of 1.0 ng/ml human IFN-gamma.
Description	IFNGR2 Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P38484.
Species	Human
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P38484
Construction	Ser28-Gln247
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	IFNGT1, IFNGR2
Research Background	IFN-gamma Receptor II, also known as IFNGR2 and IFNGT1, is a transmembrane protein belonging to the type II cytokine receptor family. IFNGR2 is a non-ligand-binding beta chain of the IFN-gamma receptor. It is an integral part of the IFN-gamma signaling transduction pathway and is likely to interact with GAF, JAK1 and JAK2. Defects in IFNGR2 are a cause of autosomal recessive Mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

Chemical Properties

Molecular Weight

38~40 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.