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hGPR91 antagonist 3

🥰Excellent
Catalog No. T62858Cas No. 1314796-31-0

hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.

hGPR91 antagonist 3

hGPR91 antagonist 3

🥰Excellent
Purity: 99.347%
Catalog No. T62858Cas No. 1314796-31-0
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.
Pack SizePriceAvailabilityQuantity
1 mg$132In Stock
5 mg$328In Stock
10 mg$545In Stock
25 mg$879In Stock
50 mg$1,190In Stock
100 mg$1,630In Stock
200 mg$2,190In Stock
1 mL x 10 mM (in DMSO)$332In Stock
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Purity:99.347%
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Product Introduction

Bioactivity
Description
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be effective in the treatment of hypertension, autoimmune disease, and retinal angiogenesis.
Targets&IC50
GPR91 (human):35 nM, GPR91:135 nM (Rat)
Chemical Properties
Molecular Weight458.41
FormulaC23H18F4N4O2
Cas No.1314796-31-0
SmilesO=C(NCC=1ON=C(C1)C=2C=CC(F)=C(C2)C(F)(F)F)CCCC=3N=C4N=CC=CC4=CC3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (174.52 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1815 mL10.9073 mL21.8145 mL109.0727 mL
5 mM0.4363 mL2.1815 mL4.3629 mL21.8145 mL
10 mM0.2181 mL1.0907 mL2.1815 mL10.9073 mL
20 mM0.1091 mL0.5454 mL1.0907 mL5.4536 mL
50 mM0.0436 mL0.2181 mL0.4363 mL2.1815 mL
100 mM0.0218 mL0.1091 mL0.2181 mL1.0907 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

GPR91
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