Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology.
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Description | Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Pomalidomide-PEG3-azide |
Molecular Weight | 488.457 |
Formula | C21H24N6O8 |
CAS No. | 2267306-15-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pomalidomide-PEG3-azide 2267306-15-8 Pomalidomide PEG3 azide PomalidomidePEG3azide Pomalidomide-PEG-3-azide inhibitor inhibit