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Anti-Aminopeptidase N/CD13 Antibody (8T921) (Synonyms: P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) amino...)

Catalog No. TMAY-00184 Copy Product Info
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Anti-Aminopeptidase N/CD13 Antibody (8T921) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (8T921) can be used in ELISA,IHC-P,WB.

Anti-Aminopeptidase N/CD13 Antibody (8T921)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00184
Synonyms P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase

Anti-Aminopeptidase N/CD13 Antibody (8T921) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (8T921) can be used in ELISA,IHC-P,WB.

Anti-Aminopeptidase N/CD13 Antibody
(8T921)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Aminopeptidase N/CD13 Antibody (8T921) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (8T921) can be used in ELISA,IHC-P,WB.
SynonymsP150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase
Ig Type
Rabbit IgG
Clone
8T921
Reactivity
Human
Specificity
Human CD13
Verified Activity
1. Immunochemical staining of human ANPEP in human renal carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human ANPEP in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
3. Anti-ANPEP rabbit monoclonal antibody at 1:500 dilution.
-Lane A: THP1 Whole Cell Lysate.
-Lane B: U937 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:110 kDa.
-Observed band size:140 kDa
Application
Recommended Dose
WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD13 / ANPEP (rh CD13 / ANPEP; TMPY-00665; NP_001141.2; Lys 69-Lys 967, 603 Met/Ile).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD13 / ANPEP protein (TMPY-00665)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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