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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

(Synonyms: M Proteinase, 3CL Proteinase) Copy Product Info

Synonyms: M Proteinase, 3CL Proteinase

Catalog No. TMPJ-01448 Copy Product Info
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$957-10 days7-10 days
10 μg$1537-10 days7-10 days
20 μg$2467-10 days7-10 days
50 μg$4657-10 days7-10 days
100 μg$7677-10 days7-10 days
200 μg$1,2707-10 days7-10 days
500 μg$2,4807-10 days7-10 days
1 mg$3,7207-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
Species
2019-nCoV
Expression System
E. coli
TagN-6xHis
Accession NumberP0DTC1
Amino AcidSer3264-Gln3569
ConstructionSer3264-Gln3569
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
FormulationSupplied as a 0.2 μm filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsM Proteinase, 3CL Proteinase
Research Background
Chemical Properties
Molecular Weight33 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) chemical structure | 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) molecular weight