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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

Catalog No. TMPJ-01448
Synonyms: M Proteinase, 3CL Proteinase

The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 154.00
50 μg 5 days $ 465.00
500 μg 5 days $ 2,480.00
1 mg 5 days $ 3,720.00
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Biological Description
Technical Params
Product Properties
Description The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
Species 2019-nCoV
Expression System E. coli
Tag N-6His
Accession Number P0DTC1
Synonyms M Proteinase, 3CL Proteinase
Amino Acid Ser3264-Gln3569
Construction Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser3264-Gln3569 is expressed with a 6His tag at the N-terminus
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 33 KDa, reducing conditions
Formulation Supplied as a 0.2 μm filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

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Keywords

3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) M Proteinase 3CL Proteinase recombinant recombinant-proteins proteins protein

 

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