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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)
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3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

Catalog No. TMPJ-01448
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 μg$1547-10 days
50 μg$4657-10 days
500 μg$2,4807-10 days
1 mg$3,7207-10 days
Bulk & Custom
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Biological Description

Description
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
Species
2019-nCoV
Expression System
E. coli
TagN-6xHis
Accession NumberP0DTC1
Synonyms
M Proteinase,3CL Proteinase
Amino Acid
Ser3264-Gln3569
Construction
Ser3264-Gln3569
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight33 KDa (reducing condition)
FormulationSupplied as a 0.2 μm filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.