3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

Catalog No. TMPJ-01448

The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.

3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)

Catalog No. TMPJ-01448

Pack Size	Price	Availability
5 μg	$95	7-10 days
10 μg	$153	7-10 days
20 μg	$246	7-10 days
50 μg	$465	7-10 days
100 μg	$767	7-10 days
200 μg	$1,270	7-10 days
500 μg	$2,480	7-10 days
1 mg	$3,720	7-10 days

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COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is P0DTC1.
Species	2019-nCoV
Expression System	E. coli
Tag	N-6xHis
Accession Number	P0DTC1
Synonyms	M Proteinase,3CL Proteinase
Amino Acid	Ser3264-Gln3569
Construction	Ser3264-Gln3569
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	33 KDa (reducing condition)
Formulation	Supplied as a 0.2 μm filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.