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1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

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Catalog No. T38593Cas No. 120693-52-9

Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone, a quinolone alkaloid derived from [Evodia rutaecarpa], is a potent angiotensin II receptor antagonist with an IC50 value of 48.2 μM.

1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

😃Good
Catalog No. T38593Cas No. 120693-52-9
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone, a quinolone alkaloid derived from [Evodia rutaecarpa], is a potent angiotensin II receptor antagonist with an IC50 value of 48.2 μM.
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Product Introduction

Bioactivity
Description
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone, a quinolone alkaloid derived from [Evodia rutaecarpa], is a potent angiotensin II receptor antagonist with an IC50 value of 48.2 μM.
Targets&IC50
Ang II receptor:48.2 μM (IC50)
In vitro
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone acts as an angiotensin II receptor antagonist with an IC50 of 48.2 μM[1].
Chemical Properties
Molecular Weight365.55
FormulaC25H35NO
Cas No.120693-52-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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