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PI3K-IN-31
🥰Excellent
Catalog No. T62470Cas No. 1359956-12-9
PI3K-IN-31 (Compound 6b) is a potent PI3K inhibitor with IC50 values of 3.7 nM for PI3Kα, 74 nM for PI3Kβ, 14.6 nM for PI3Kγ, and 9.9 nM for PI3Kδ. PI3K-IN-31 has demonstrated anticancer activity.
PI3K-IN-31
🥰Excellent
Catalog No. T62470Cas No. 1359956-12-9
PI3K-IN-31 (Compound 6b) is a potent PI3K inhibitor with IC50 values of 3.7 nM for PI3Kα, 74 nM for PI3Kβ, 14.6 nM for PI3Kγ, and 9.9 nM for PI3Kδ. PI3K-IN-31 has demonstrated anticancer activity.
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Product Introduction
Bioactivity
Chemical Properties
| Description | PI3K-IN-31 (Compound 6b) is a potent PI3K inhibitor with IC50 values of 3.7 nM for PI3Kα, 74 nM for PI3Kβ, 14.6 nM for PI3Kγ, and 9.9 nM for PI3Kδ. PI3K-IN-31 has demonstrated anticancer activity. |
| Targets&IC50 | PI3Kα:3.7 nM, PI3Kγ:14.6 nM, PI3Kδ:9.9 nM, PI3Kβ:74 nM |
| Molecular Weight | 435.43 |
| Formula | C19H23F2N7O3 |
| Cas No. | 1359956-12-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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