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CD20 Protein, Human, Recombinant (His & Avi)

(Synonyms: S7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1) Copy Product Info

Synonyms: S7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1

Catalog No. TMPK-00183 Copy Product Info
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$56-In Stock
10 μg$88-In Stock
20 μg$1437-10 days7-10 days
50 μg$278-In Stock
100 μg$4657-10 days7-10 days
200 μg$8397-10 days7-10 days
500 μg$1,850-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Description
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
Species
Human
Expression System
E. coli
TagC-His-Avi
Accession NumberP11836-1
ConstructionIle141-Ser188
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM PB, 10% Glycerol, 0.4M Urea, 1 mM GSH, 0.1 mM GSSG (pH 7.0).
Stability & StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsS7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1
Research Background
Chemical Properties
Molecular Weight16.8 kDa (predicted) same as Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: CD20 Protein, Human, Recombinant (His & Avi) chemical structure | CD20 Protein, Human, Recombinant (His & Avi) molecular weight