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CD20 Protein, Human, Recombinant (His & Avi)

(Synonyms: S7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1) Copy Product Info

Synonyms: S7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1

Catalog No. TMPK-00183 Copy Product Info
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$56-In Stock
10 µg$88-In Stock
20 µg$1437-10 days7-10 days
50 µg$278-In Stock
100 µg$4657-10 days7-10 days
200 µg$8397-10 days7-10 days
500 µg$1,850-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human CD20, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 0.33μg/ml determined by ELISA.
Description
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. CD20 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. The predicted molecular weight is 16.8 kDa and the accession number is P11836-1.
Species
Human
Expression System
E. coli
TagC-His-Avi
Accession NumberP11836-1
ConstructionIle141-Ser188
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM PB, 10% Glycerol, 0.4M Urea, 1 mM GSH, 0.1 mM GSSG (pH 7.0).
SynonymsS7, MS4A2, MS4A-1, MS4A1, Ly-44, LEU-16, CVID5, CD20S7, CD20 receptor, CD20, Bp35, B1
Research Background
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.
Chemical Properties
Molecular Weight16.8 kDa (predicted) same as Tris-Bis PAGE result.
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CD20 Protein, Human, Recombinant (His & Avi) chemical structure | CD20 Protein, Human, Recombinant (His & Avi) molecular weight