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HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

(Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ERBB3) Copy Product Info

Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ERBB3

Catalog No. TMPK-01280 Copy Product Info
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number is XP_005571238.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$517-10 days7-10 days
10 µg$807-10 days7-10 days
20 µg$1297-10 days7-10 days
50 µg$2487-10 days7-10 days
100 µg$4187-10 days7-10 days
200 µg$7577-10 days7-10 days
500 µg$1,6707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Cynomolgus/Rhesus macaque Her3, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Her3 Antibody, hFc Tag with the EC50 of 20.1ng/ml determined by ELISA.
Description
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number is XP_005571238.1.
Species
Cynomolgus,Rhesus
Expression System
HEK293 Cells
TagC-His
Accession NumberXP_005571238.1
ConstructionSer20-His641
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymsp85-sErbB3, p45-sErbB3, p180-ErbB3, MGC88033, MDA-BF-1, LCCS2, HER3c-erbB-3, HER3, ErbB-3, ERBB3
Research Background
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Chemical Properties
Molecular Weight69.54 kDa (predicted). Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) chemical structure | HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) molecular weight