Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 418.00 | |
500 μg | 5 days | $ 1,670.00 | |
1 mg | 5 days | $ 2,800.00 |
Description | Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
Species | Cynomolgus,Rhesus macaque |
Expression System | HEK293 |
Tag | C-His |
Accession Number | XP_005571238.1 |
Synonyms | p85-sErbB3, HER3, LCCS2, p180-ErbB3, HER3c-erbB-3, ErbB-3, ERBB3, MDA-BF-1, MGC88033, p45-sErbB3 |
Construction | Recombinant Cynomolgus/Rhesus macaque Her3 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ser20-His641.[Accession |XP_005571238.1/G7N7B1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 69.54 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
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Please read the User Guide of Recombinant Proteins for more specific information.
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) p85-sErbB3 HER3 ERBB 3 MGC-88033 MGC 88033 HER-3 LCCS-2 LCCS2 p180-ErbB3 HER3c-erbB-3 ErbB-3 ERBB3 MDA-BF-1 LCCS 2 MGC88033 HER 3 p45-sErbB3 recombinant recombinant-proteins proteins protein