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HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Catalog No. TMPK-01280
Synonyms: p85-sErbB3, HER3, LCCS2, p180-ErbB3, HER3c-erbB-3, ErbB-3, ERBB3, MDA-BF-1, MGC88033, p45-sErbB3

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

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HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).
Species Cynomolgus,Rhesus macaque
Expression System HEK293
Tag C-His
Accession Number XP_005571238.1
Synonyms p85-sErbB3, HER3, LCCS2, p180-ErbB3, HER3c-erbB-3, ErbB-3, ERBB3, MDA-BF-1, MGC88033, p45-sErbB3
Construction Recombinant Cynomolgus/Rhesus macaque Her3 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Ser20-His641.[Accession |XP_005571238.1/G7N7B1]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 69.54 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

References and Literature

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Keywords

HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) p85-sErbB3 HER3 ERBB 3 MGC-88033 MGC 88033 HER-3 LCCS-2 LCCS2 p180-ErbB3 HER3c-erbB-3 ErbB-3 ERBB3 MDA-BF-1 LCCS 2 MGC88033 HER 3 p45-sErbB3 recombinant recombinant-proteins proteins protein

 

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